As an efficient, energy-saving and environmentally friendly granulation equipment, dry granulator has been widely used in pharmaceutical, food and chemical fields. However, the optimization of process parameters and product quality control of dry granulators are crucial aspects of the production process. In this article, the process parameter optimization and product quality control of the dry granulator will be optimized.
1. Optimization of process parameters
1.The nature of the material
Material properties are the key factors affecting the effect of dry granulation. Understanding the physical and chemical properties of the material, such as particle size, moisture content, viscosity and adsorption, can help to select the appropriate process parameters and improve the granulation results.
2.Pressure and speed
The pressure and speed of the dry granulator are important parameters that affect the granulation effect. Proper pressure and speed can increase the density and strength of the particles and reduce the wear of the particles. In actual production, the pressure and speed should be reasonably adjusted according to the nature of the material and the product requirements.
3.Granulation temperature
The granulation temperature has a significant effect on the dry granulation effect. Too high a temperature may cause the material to decompose or deteriorate, while too low a temperature may result in insufficient particle strength. Therefore, the granulation temperature should be reasonably controlled according to the thermal stability of the material during the production process.
4.Particle shape and size
Particle shape and size are important factors that affect product quality. By adjusting components such as knives and screens of the dry granulator, the shape and size of the particles can be controlled to meet product requirements.
2. Product quality control
1.Detection method
The quality of dry granulation products is tested, including particle shape, particle size distribution, density, hardness, solubility and other indicators. Commonly used detection methods include microscopic observation, laser particle size analysis, density meter measurement and hardness test.
2.Production process control
In the production process, the operation status of the dry granulator should be monitored in real time to ensure the stability of process parameters. At the same time, strict quality inspection of raw materials and finished products is carried out to prevent substandard products from entering the market.
3.Equipment maintenance and maintenance
The equipment maintenance and maintenance of the dry granulator is of great significance to the quality control of the product. Regularly inspect and maintain equipment to ensure that the equipment is operating properly and reduce the impact of equipment failure on product quality.
4.Operator training
Improve the professional quality and operation skills of operators, ensure that they can master the process parameter adjustment and product quality control methods of dry granulators, and reduce the impact of human factors on product quality.