Radiation** is one of the main means of tumor**.
About 75% and 80% of patients with malignant tumors require radiation at some stage.
Tomotherapy, also known as the "Tomo Knife", is an advanced image-guided radiotherapy device.
TOMO integrates a 6mV accelerator into a CT rack and is one of the most advanced radiotherapy devices in the modern era under the guidance of CT images.
TOMO has a wide range of clinical applications, and can be used in a non-invasive, frameless stereotactic manner with precision as small as 0single or multiple small intracranial and extracranial tumor lesions of about 6 cm;
It can also perform image-guided intensity-modulation** (e.g., whole cerebrospinal cord and whole-body bone marrow intensity-modulated irradiation) for large tumors with a diameter of 60 cm in diameter and a large tumor in a body length of 150 cm.
Its indications cover almost all cases suitable for radiation**, especially those with intensity-modulated **.
So, what are the benefits of choosing TOMO**? 
01 Tomo Knife - Large-scale precision radiotherapy.
In the late 80s of the 20th century, Mackie proposed the concept of tomotherapy.
The research team wanted to use a slip ring frame structure for CT, and a dose detection system could be installed to perform CT scans at the same time as radiotherapy.
The TOMO Radiation** system mounts a 6mV linear accelerator directly on the CT slip ring frame, and the narrow sector irradiation can also be irradiated by 360-degree continuous rotation around the center of the machine.
At the same time as the rack rotates, the ** bed can enter the bed according to the center of the rack, and the irradiated field rays can produce a spiral irradiation flux map around the ** patient.
Conventional accelerators, on the other hand, can only irradiate from a few fixed fields.
The system can also observe the changes of tumors and normal tissues at any time during radiotherapy, and quickly modify and adjust the ** plan for adaptive radiotherapy.
The helical tomotherapy system has a larger range than the traditional accelerator, and can complete the precision radiotherapy of various parts, and it is also the only radiation equipment that can complete the whole central irradiation, whole bone marrow irradiation and multiple radiation targets at the same time.
02 What are the advantages of Tomo Knife compared to traditional radiotherapy?
TOMO is a relatively advanced radiotherapy technology, what are its advances compared to traditional radiotherapy?
1.High precision.
The imaging source and irradiation source of the TOMO knife are the same, the mechanical accuracy is the same, and the imaging accuracy and illumination are both 01mm, which is much higher than the 1mm of conventional accelerators.
2.The ability to do fast calculations.
The use of super server clusters provides Tomo Knife with extraordinary computing power.
TOMO Knife is currently the only image-guided radiotherapy system using CT, with higher imaging accuracy and fast speed, so that image-guided radiotherapy can be carried out instantly.
3.Higher tumor conformability and dose uniformity.
The TOMO Knife is the only radiotherapy system that can use CT image guidance, which can obtain the best ray path to suit the tumor under the condition that the tumor shape is known, so that the dose within the target area can achieve a high degree of uniformity, and better protect normal tissues and organs.
03 What is the clinical effect of Tomo Knife?
The PLA General Hospital summarized the results of 190 patients with nasopharyngeal carcinoma who received TOMO radiotherapy from 2007 to 2012.
Among them, 31 patients received TOMO radiotherapy alone, 129 patients received platinum-based chemotherapy combined with radiotherapy, and 30 patients received concurrent EGFR monoclonal antibody combined with radiotherapy.
PGTVNX and PGTVND were prescribed at doses 70 74GY 33F, and the adverse reactions of acute radiotherapy were all grade 1 or 2, and no adverse reactions of grade 3 or higher were reported.
The median follow-up time was 32 months, and the 3-year local** survival rate (LRFS), regional** survival rate (NRFS), distant metastasis-free survival (DMFS) and overall survival (OS) of TOMO** patients in the whole group were respectively. 0% and 863%[1]。
The investigators were quite satisfied with the results of the 3-year survival rate of nasopharyngeal carcinoma newly diagnosed with TOMO**, and the toxicity of acute chronic radiotherapy was very low.
DU et al. also summarized that 132 patients with newly diagnosed nasopharyngeal carcinoma in 2011 and 2013 conducted a phase II clinical study.
The results showed that the 2-year local** survival rate was 967%, and the region-free survival rate was 955%, the survival rate without distant metastasis was 927% and an overall survival rate of 932%。
Leung SW et al. summarized the 5-year experience of TOMO radiotherapy for nasopharyngeal carcinoma.
The results showed that the 5-year local control rate was as high as 97%, and the survival rate without distant metastasis was 846%。
Late adverse reactions were mild and showed good long-term clinical outcomes.
Overall, compared with traditional radiotherapy, Tomo Knife is an advanced, safe and efficient radiotherapy technique. Collapse.