Mr. Feng, 35 years old, loves seafood and has seafood at almost every mealRecently, there was joint redness and swelling, accompanied by painful sensations, especially the pain in the big toe, Mr. Feng thought it was caused by mosquito bites, and did not care about it after self-treatment, but these symptoms were not alleviated, and Mr. Feng found that his joints had abnormal lumps, which severely limited joint movementThese symptoms have clearly affected Mr. Feng's life, and he decided to go to the hospital.
Through the consultation, we learned that Mr. Feng has poor eating habits, especially prefers to eat meat, seafood and other high-purine foods, and usually has high pressure in work and life, irregular diet, and insufficient exercise; Through physical examination, it was found that Mr. Feng was 170 cm tall, weighed 90 kg, and had a high body fat percentage
We had a palpation of Mr. Feng's big toe joint, and the joint mass was unusually hard, which was in line with the basic characteristics of tophi, and we decided to examine it further; Through biochemical tests, we found that uric acid levels were elevated, reaching 600umol l, body mass index (BMI) 28,Falls into the category of obesity,joint x-ray showing of uric acid arthritis; Through clinical symptoms and examination results, Mr. Feng was diagnosed with hyperuricemia complicated by joint tophi.
We informed Mr. Feng of the results of the examination and provided him with health educationMr. Feng often eats "purine big" foods to lead to hyperuricemia, Mr. Feng regrets it very much, and then we formulated a ** plan for him, Mr. Feng needs to carry out dietary conditioning, give patients low-purine diet guidance, avoid high-purine foods, and increase the intake of vegetables and fruits;
At the same time, exercise guidance is carried outPatients are recommended to perform appropriate aerobic exercise under the guidance of a doctor, and according to the specific situation of the patient, the urate-lowering drug febuxostat is recommended, and patients with high body fat need to be managed for weight.
Through a period of time, Mr. Feng's uric acid has dropped to the normal range, the joint symptoms have been alleviated, and the quality of life has also been improved, through Mr. Feng's case, we can know that hyperuricemia is a group of diseases caused by the disorder of uric acid excretion pathways in the body, excessive production or intake of too many purine foods.
The disease is characterized by hyperuricemia, which is prone to cause complications such as gout and uric acid arthritis, and can effectively alleviate the patient's symptoms and control the development of the disease through dietary conditioning, reasonable exercise, medication** and weight management. Among them, dietary adjustment is very important, and long-term eating of high-purine foods has many negative effects, so let's learn more about them below.
1) Elevated uric acid levels
Purine is a chemical found in animal tissues and certain plants, when the body digests purine food, uric acid is produced, and long-term intake of too much high-purine food can lead to an increase in uric acid levels in the body. Hyperuricemia increases the risk of gout and uric acid nephropathy.
Uric acid is the end product of human metabolism, most of which is excreted by urine, but when uric acid is produced excessively, it will accumulate in the body, resulting in abnormal uric acid content in the body, causing diseases such as gout and uric acid nephropathy.
2) Gout
Uric acid crystals are not easy to dissolve in a low temperature environment, while the temperature of the joints is low relative to other parts, and uric acid crystals enter the joint fluid or are not easy to be excreted by the bodyHence the formation of gout.
When a gout attack,Patients often have severe joint pain, redness and swelling, local fever and other symptoms, which affect the quality of lifeMeasure.
Chronic gout greatly reduces the comfort of patients' lives, especially when joint pain is severe, and even affects daily life and work. Therefore, long-term intake of high-purine foods can increase the risk of gout, which can have serious effects on health.
3) Kidney stones
Excessive accumulation of urate in the body will form uric acid stones, which are mostly accumulated in the kidneys and can also be deposited in the urinary tract system, and long-term intake of high-purine foods will increase the risk of uric acid stone formation, affecting the health of the kidneys and urinary system
Uric acid stones usually cause severe pain, hematuria, frequent urination, urgency and other symptoms, which bring great distress to patients and also increase the incidence of urinary tract infections. Therefore, long-term intake of high-purine foods has a certain promoting effect on the production of uric acid stones.
4) Cardiovascular disease
Studies have shown that blood uric acid is 59 per elevation5 mol l, the risk of death increased by 48% in men and 126% in women. Another study found that the mortality rate in people with 433 mol of uric acid was 5 times higher than that of people with 303 mol of uric acidBecause uric acid can trigger endothelial cell dysfunction and inflammation of the blood vessel wall, leading to the progression of atherosclerosis and other pathologies.
Long-term consumption of high-purine foods will increase the risk of cardiovascular disease, in order to prevent these potential risks, people should properly control the intake of high-purine foods, maintain good eating habits and lifestyles, and maintain health of the body.
Kind. Organ meats
These foods are extremely high in purines, and if consumed regularly, they are likely to increase the concentration of uric acid in the body, resulting in an increase in uric acid. Offal foods are not only high in purines, but also high in fat, which has a certain negative impact on human healthTherefore, animal offal, which is known as the "big purine household", although delicious, should also be reminded that it should not be consumed in excess.
Offal foods mainly include pork liver, chicken liver, duck liver, etc., of which the purine content of pork liver has reached 2752mg kg. Otherwise, it will bury hidden dangers to your health.
Secondly, the fat content of animal offal cannot be ignored. Fat is one of the main causes of cardiovascular and cerebrovascular diseases, and the fat content in animal offal is very high, if it is eaten regularly, it will increase the accumulation of body fat, increase the risk of cardiovascular disease, and its own high-purine food will increase the risk of cardiovascular disease, so long-term eating of high-purine and high-fat food has a huge negative impact on cardiovascular disease.
Animal offal also contains a variety of metabolic wastes and microbial toxins, and long-term excessive consumption will also have a negative impact on human health. These metabolic wastes and microbial toxins accumulate too much in the human body, causing a burden on the internal organs of the body.
Kind. Fish, shrimp, crab shellfish
These foods are known as "purine giants" mainly because they are rich in purine substances.
Excessive purine intake can lead to an increase in uric acid, which can have adverse effects on human health. We should eat fish, shrimp, crabs and shellfish in moderation in our daily diet to avoid excessive purine intake and protect our health.
Fish contain less purines, but some deep-sea fish have higher purine content, and most of the shellfish foods belong to the purinesThe high content of mussel meat, up to 4135MK kg, is delicious, but excessive consumption will increase the burden of uric acid in the body and cause a series of chronic diseases.
The above-mentioned Mr. Feng is a seafood lover, who has suffered from hyperuricemia and gout symptoms after eating seafood for a long time, which seriously affected his daily life, and it was found that it was caused by long-term eating of seafood through examination. Therefore, people who love fish, shrimp, crab and shellfish should control the amount of food they eat and avoid excessive intake of purines to reduce the risk of gout.
Kind. Dried fungi and algae
These foods are rich in many nutrients, but they are also classified as high-purine foods. Excessive intake will have adverse effects on our health, and we should control the amount of food we consume appropriately. Dried fungi and algae foods mainly include dried shiitake mushrooms, seaweed, etcThese ingredients are rich in fiber, vitamins and other nutrients, which have a positive effect on human healthHowever, the purine content in dried fungal algae food is also high, especially in some fermented or pickled dried fungal algae food, which has a higher purine contentTherefore, in our daily diet, we should be vigilant about the purine content of dried fungal algae foods and control their consumption appropriately.
Among them, seaweed has a higher purine content than mussel meat and pork liverTherefore, we should appropriately control the amount of dried fungal and algae food, especially for people with a history of uric acid-related diseases. For people who have eaten high-purine foods for a long time and have related symptoms, it is recommended to go to the hospital for examination in time and receive ** as soon as possible.
1.Uric acid determination
A test to measure the level of uric acid in the urine or blood can be done with a simple blood test or urine test.
The measurement of serum uric acid value is a routine means to evaluate hyperuricemia and gout, uric acid is a product of purine metabolism, so uric acid level is an important indicator to assess the status of purine metabolism, eating high-purine foods will increase the production of uric acid, and at the same time, uric acid excretion disorders may also lead to elevated uric acid. Uric acid measurement allows for early knowledge of uric acid levels so that timely measures can be taken to control them.
2.X-rays of the joints
Severe joint pain, redness, swelling, and limited movement may require joint x-rays
Mr. Feng often eats seafood and has symptoms such as joint pain, and through X-ray examination, he can evaluate the structural changes of bones and joints and help diagnose whether he has arthritis or gout and other related conditions.
3.Renal function tests
Long-term intake of high-purine foods may trigger kidney-related problems such as uric acid stones, so it is important to check kidney function。Renal function tests include the measurement of serum creatinine, uric acid and other indicators, and imaging examinations such as B-ultrasound or CT can also be used to understand the condition of the kidneys and detect early lesions of kidney disease.
4.Echocardiology**
Hyperuricemia is closely related to cardiovascular disease, and patients with gout have a significantly increased risk of cardiovascular disease
In this case, echocardiology** can be used to evaluate the structure and function of the heart, understand the condition of the heart muscle, and diagnose the condition of heart disease.
These examination items can help detect the lesions of hyperuricemia and gout and other related diseases in time, and are of great significance for early understanding and intervention in the physical condition and taking the best measures. Therefore, it is advisable to keep abreast of your physical condition in case of uncomfortable symptoms.
The three foods of animal offal, fish, shrimp, crab shellfish, dried fungi and algae may increase uric acid, and no matter how much you like to eat it, you must keep your mouth shut. Mr. Feng mentioned above especially likes to eat seafood, which eventually leads to hyperuricemia and gout, which has a serious impact on his life, in daily life, we must pay attention to our eating habits and never let our eating habits have a negative impact on the body.
Literature Reference:1.Xing Yuting, Zhang Jinsong, Han Juanjuan, etc. A study of the association between high-purine food intake and cardiovascular disease. Chinese Journal of Cardiovascular, 2017, 45(9): 766-770
2.Liu Jiali, Li Yiyong, Du Xiaofei, etc. Research progress on the association between high-purine foods and cardiovascular diseases. Chinese Journal of Preventive Medicine, 2018, 52(4): 412-416