Application of Bacillus coagulans in pets
Highlights of this issue
Bacillus coagulans and pet intestinal health.
Bacillus coagulans and pet immunomodulation.
Bacillus coagulans and pet oral health.
Bacillus coagulans and pet joint care.
Preface. Pets play an important role in the daily life of humans, and their health is becoming more and more concerned by pet owners. Probiotics refer to live microorganisms that can improve the balance of microorganisms in the intestinal tract of the host, which is very beneficial to the health of animals. Among them, Bacillus coagulans has the characteristics of high temperature resistance and lactic acid production, which has a positive impact on pet immune regulation, joint inflammation, intestinal infection and oral health, and is widely used in pet food and health products.
1. Bacillus coagulans and pet intestinal health care.
Pets (mainly domestic dogs and cats) play an important role in the daily life of humans, and their health is a growing concern for pet owners. The use of Bacillus coagulans in pet food can help regulate your pet's immune system, help prevent inflammation of your pet's joints, prevent infections caused by intestinal pathogens, and maintain your pet's oral health.
Fig.1 Mechanism of action of probiotics on the intestinal mucosal barrier.
*: A Ai Baheti, Wu Ruiyun, Xiao Mengyuan, Li Pinglan, Tan Chunming
2. Bacillus coagulans and pet immunomodulation.
Bacillus coagulans can also exert immunomodulatory effects. The main mechanism of action is that Bacillus coagulans in the intestine can directly or indirectly affect the function of various immune cells such as monocytes, macrophages, T cells, B cells, and natural killer cells, thereby playing a role in regulating immunity and controlling inflammation (Fig. 2). Not only that, but Bacillus coagulans can also affect the immune system by regulating signal transduction.
Fig.2 Mechanism of probiotic immune response to intestinal tract.
*: A Ai Baheti, Wu Ruiyun, Xiao Mengyuan, Li Pinglan, Tan Chunming
3. Bacillus coagulans and pet oral health.
Oral problems are one of the most common diseases in pets. According to the American Veterinary Medical Association (**MA), oral health is one of the top three concerns for pet owners, with about 80% of dogs suffering from some form of oral disease by the age of three.
Oral diseases seriously affect the teeth and gums of pets, and the breeding of bacteria in the oral cavity will cause periodontal disease, make pets painful, and seriously affect the normal eating of pets, resulting in loss of appetite and emaciation. At the same time, bacteria in the mouth can also affect pets' heart, liver, kidneys and other organs through the blood, resulting in a series of bacterial diseases, which are life-threatening in severe cases. Therefore, maintaining good oral health contributes to your pet's health as well as daily life. Daily supplementation with foods containing Bacillus coagulans can reduce the occurrence of tooth decay and improve periodontal disease.
Fig.3 Application of probiotics in pet mouth.
3. Bacillus coagulans and pet joint health.
Pet joint problems occur at all stages of the pet. At an early age, due to the rapid weight gain, it is easy to put a burden on the bones and joints. In adulthood, active pets are prone to wear and tear due to their high energy and increased exercise. In old age, due to the massive loss of calcium, osteoporosis and joint degeneration. In addition to this, some large dogs and obese pets are more likely to suffer from joint problems.
Studies have shown that the gut microbiota helps maintain the integrity of the intestinal barrier. The gut microbiota can influence the absorption of calcium and vitamin D, the maturation of the immune system, and the production and activation of hormones such as estrogen and androgen. These factors affect the growth and development of joints. In addition, when the intestinal flora is dysbiosis, it leads to the production of inflammatory cytokines, which translocates the intestinal barrier and has a detrimental effect on the bone, which seriously leads to osteoporosis (Figure 4). Taking probiotics (Bacillus coagulans, etc.) and prebiotics can alleviate or restore bone health.
Fig. 4 Potential relationship between gut microbiota and osteoporosis.
*：li, boer, oei, &medina-gomez (2021)