In 2023, Avalan has sent doctors with rich clinical experience to the international stage, in the past, we rarely had international forums for regenerative medical aesthetics, almost all of them were special sessions for hyaluronic acid, and even fewer doctors went abroad to share their clinical experience in the use of facial acupuncture. Now, with Avalan, what we were looking forward to has finally come true.
Previous post:The first bullet of the differentiation of Tongyan Needle is coming: Avalan won at the starting line, and today I will continue to talk about the differences between Avalan in manufacturing process and clinical effect.
Advantages of the manufacturing process
As we all know, Avalan uses a series of patented technologies to produce solid microspheres with uniform size and smooth surface, which not only do not need to be reconstituted for a long time like traditional rejuvenation injections, which increases the risk of infection, but also avoids the formation of foam, which has some particles in it, which may not only clog the needle, but also increase the risk of nodules.
Solid microspheres are also able to maintain long-term stability for up to two years. Other Korean Tongyan needles use a porous microsphere structure, which degrades quickly, and Avalan degrades the body, that is, the inside and outside are degraded together, so that the degradation rate of Avalan's PLLA can be controlled to a uniform degradation rate, and the microsphere structure is maintained for a longer time and the effect is more sustainable.
An important part of the process is actually controlling the rate of degradation of the microspheres. Let's take a look at the degradation rate of a Korean Tongyan needle, the following figure is from Reference 1, which is about the degradation of a Korean Tongyan needle microsphere (400 times light mirror observation), we can see that the microsphere structure is intact 4 weeks after injection, and part of the microsphere structure can be degraded 20 weeks after injection
And there is a patented technology in the manufacturing process of Avalan called ——Patented Tri-H series technology, which controlled the uniform degradation of the microspheres over a period of 2 years (106 weeks). That is to say, during these 2 years, the degradation rate of Avalan microspheres remains uniform and uniform, which means that the clinical effect is stable: there will be no particularly long effect in some people and a particularly short effect in others. It's a bit like a "slow-release" effect, which is to continuously exert a stable regenerative effect, achieving stable collagen growth and low inflammation in the body, achieving a gradual, natural effect.
Figure: Degradation curves of Avalan.
Rethinking the effect of injections
Finally, clinical feedback shows that the previous idea is that poly-L-lactic acid is mainly to promote the synthesis of collagen and then expand the volume of tissues, and even fear that the meat will grow forever after the injection. However, in the process of using a large number of people for more than a year, everyone feels that compared with microfilling, the effect of Avalan is more reflected in the improvement of ** function, such as ** firming, improvement of skin texture, improvement of overall contour and smoothness of facial curves. This makes me think".ActivityRegenerationThe word. While solving the problem of capacity loss, many beauty seekers unexpectedly found that their ** has become better, and the problem of pigmentation has actually improved, and this improvement is almost the overall synchronous rejuvenation, not just filling. Therefore, this is also one of the reasons why Avalan currently has a good reputation on social platforms.
Case**: Dr. Huang Rong (pay attention to the improvement of melasma).
It is precisely because Avalan has perfected the method of compounding and injection, reducing the redness and swelling of injection, promoting the recovery of tissue function, and the obvious difference in safety and effect from traditional PLLA, which has changed the previous market performance of polylactic acid, so it has been recognized by doctors and beauty seekers. Functionally speaking, regenerative medical aesthetic products are a good supplement to previous fillers such as hyaluronic acid and collagen, because not everyone needs large-volume filling, and some beauty seekers need firming and lifting, natural anti-aging, and even older beauty seekers need to tighten and fill in flowers-".Firming and lifting first, then filling
References. 1. lin cy, lin jy, yang dy et al. efficacy and safety of poly-d,l-lactic acid microspheres as subdermal fillers in animals.plast aesthet res 2019; 6: 16.
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