This article is from "Nankai Sun Pharmacist", which is used for medical science popularization for reference. Atherosclerosis refers to the thickening and hardening of the arterial wall, the loss of elasticity, and the attachment of plaque, the shrinkage of the official lumen, resulting in obstruction of blood flow, organ ischemia, once the plaque ruptures, can form blood clots, block blood vessels, and lead to the loss of organ function. Atherosclerotic cardiovascular diseases include coronary heart disease, ischemic stroke and peripheral arterial disease, and the drugs for the prevention and treatment of atherosclerotic cardiovascular diseases mainly include isosorbide nitrate, nifedipine, metoprolol and other anti-ischemic drugs, aspirin, clopidogrel, ticagrelor and other antiplatelet drugs, statin lipid regulators and various antihypertensive drugs, etc., but these drugs have more or less certain limitations, such as isosorbide nitrate resistance, aspirin gastric mucosal damage, Genetic polymorphisms of clopidogrel, muscle toxicity of statins, and more.
Traditional Chinese medicine theory believes that the basic pathological mechanism of coronary heart disease, ischemic stroke and peripheral arterial disease is qi deficiency and blood stasis, in the past, it was believed that traditional Chinese medicine can only be used as an auxiliary in the process of atherosclerotic cardiovascular disease, but with the continuous deepening of evidence-based research on traditional Chinese medicine in recent years, traditional Chinese medicine has gradually been internationally recognized, and atherosclerotic cardiovascular disease can be used to regulate qi and blood.
Wenxin Granules: Wenxin Granules is a commonly used Chinese patent medicine in clinical practice to nourish qi, nourish yin and invigorate blood, and the formula is Codonopsis, Huangjing, and San.
7. Amber and jatamansia have the effect of nourishing qi and nourishing yin, invigorating blood and removing blood stasis, and are used for palpitations, shortness of breath and fatigue, chest tightness and chest pain caused by qi and yin deficiency, cardiac stasis, ventricular premature contractions, and atrial premature contractions in patients with the above syndromes. Animal pharmacology studies have shown that Wenxin granules can protect the heart by anti-inflammatory, anti-oxidative stress, regulate vasomotor disorders, reduce vascular endothelial damage, anti-coronary ischemia, inhibit myocardial hypertrophy and fibrosis, and have anti-arrhythmic effects. Clinical studies have confirmed that for patients without structural heart disease, Wenxin granules can effectively reduce frequent ventricular premature contractions and alleviate related symptoms. It has a good effect on angina, heart failure and arrhythmia, and can significantly improve cardiac ejection fraction. For patients with atrial fibrillation or heart failure combined with arrhythmia, Western medicine combined with Wenxin granules can obtain better efficacy. Clinically, Wenxin Granules are mainly suitable for patients with coronary heart disease with various arrhythmias as the main manifestations. In terms of safety, Wenxin granules are safe and well tolerated, and a small number of people will have adverse reactions such as nausea, vomiting, abdominal discomfort, bloating, diarrhea, abdominal pain, dizziness, headache, rash, itching, and chest tightness, without serious adverse reactions.
Tongxinluo Capsule: Tongxinluo Capsule is a clinically commonly used qi and blood invigorating Chinese patent medicine, the composition of ginseng, leech, scorpion, red peony, cicada, turtle insect, centipede, sandalwood, incense, frankincense, sour jujube kernel, borneol, with the effect of invigorating qi and invigorating blood, Tongluo and relieving pain, used for heart qi deficiency, blood stasis obstruction syndrome, symptoms of chest suffocation, tingling, colic, impulsive, palpitations and sweating, shortness of breath and fatigue, purple and dark tongue or ecchymosis, thin pulse or generation, coronary heart disease angina see the above syndromes, It can also be used for qi deficiency and blood stasis obstructive stroke, with symptoms of hemiplegia or partial numbness, crooked mouth and tongue, unfavorable speech, and stroke with the above syndromes. Experimental animal pharmacology studies have shown that Tongxinluo Capsule has anti-inflammatory, antioxidant, regulating blood lipid metabolism, stabilizing plaque, protecting vascular endothelial function, inhibiting blood vessels, ventricular remodeling, etc., and inhibiting the occurrence and development of atherosclerosis from a variety of mechanisms. Clinical studies have confirmed that Tongxinluo Capsule can alleviate angina symptoms, improve ECG ischemic manifestations, and reduce the thickness and plaque area of carotid artery intima, reduce the incidence of unstable angina, and improve clopidogrel resistance when combined with clopidogrel. Clinically, Tongxinluo Capsule can be used for coronary heart disease, angina, acute myocardial infarction, and ischemic stroke. In terms of safety, individual patients may experience stomach upset after taking the drug.
Qi Shen Yiqi Dripping Pills: Qi Shen Yiqi Dripping Pills is a commonly used Chinese patent medicine in clinical practice to invigorate qi and invigorate blood, and the formula is Astragalus membranaceus, Salvia miltiorrhizae, and San.
7. Sesame oil, which has the effect of invigorating qi and pulse, invigorating blood and relieving pain, is used for chest paralysis with qi deficiency and blood stasis. Symptoms include chest tightness and chest pain, shortness of breath and fatigue, palpitations, pale complexion, self-sweating, fat tongue with tooth marks, dark or purple tongue with ecchymosis, heavy pulse or heavy strings, suitable for coronary heart disease angina pectoris with the above syndromes. Experimental animal pharmacological studies have shown that Qishen Yiqi Dripping Pill has the effects of protecting vascular endothelial function, dilating blood vessels, anti-inflammatory, antioxidant, anti-atherosclerosis, delaying ventricular remodeling, improving cardiac function, and improving myocardial ischemia. Clinical studies have confirmed that for patients after cardiac stenting, combined with Qishen Yiqi Dripping Pill on the basis of conventional **, can reduce myocardial damage. Clinically, Qishen Yiqi Dripping Pill is especially suitable for patients with coronary heart disease combined with heart failure and coronary heart disease combined with pulmonary heart disease. In terms of safety, Qishen Yiqi Dripping Pill occasionally has gastrointestinal discomfort reactions such as nausea, vomiting, and flatulence, and rare allergic reactions such as rash, itching, and flushing.
Finally, the above three drugs can not only increase the efficacy of Western medicine, but also improve the symptoms of patients, each with its own characteristics and good safety. In addition to these three Chinese patent medicines, other Chinese patent medicines that regulate qi and blood also include fast-acting Xingxin Pills, Compound Danshen Dripping Pills, Musk Baoxin Pills, Naoxintong Capsules, Ginseng Song Yangxin Capsules, Dengzhan Shengmai Capsules, etc., which will be introduced to you in the future.