GPLD1 (GPI-specific phospholipase D1) is a phospholipase enzyme that degrades glycolipids associated with cell membranes primarily by processing and cleaving phosphatidylinositol (PI) acyl chains in mammals. GPLD1 is also a phospholipase enzyme that catalyzes selective phosphate bond cleavage during the degradation of general phosphatidyl esters. GPLD1 represents a class of highly conserved lipid enzymes that have become a key enzyme to explain the regulatory regulation of cellular events by glycolipids due to their unique phospholipase-specific activities.
Basic information about GPLD1:
Gene name: GPLD1
Protein name: GPI-specific phospholipase D1
Protein molecular weight: approx. 111 kDa
Codon sequence: contains the promoter region, the coding region, and the termination region.
Infrastructure: Promoter region plant basfusin 5'sequence, the coding region 94-96-1011-sequence, the termination region contains one stop codon.
Catalog No. PA1000-9108
Function and structure of GPLD1 protein:
As a phospholipase enzyme, GPLD1 is primarily involved in phosphatidylinositol (PI) metabolism within cells, promoting its critical role in cell biology by processing and cleaving the Pi acyl chain. At the same time, GPLD1 can also act as a phospholipase enzyme to catalyze selective phosphate ester bond cleavage during the degradation of general phosphatidates, and regulate phospholipid metabolic balance through this reaction. Its specific activity makes GPLD1 essential in physiological processes such as cell signaling, maintenance of cell membrane structure, and lipid metabolism.
The structure of GPLD1 protein mainly contains promoter region, coding region and stop region. The promoter region usually contains plant basfucin-5'sequence, which takes on the function of initiating transcription; The coding region contains 94-96-1011-sequence, which encodes the amino acid sequence of the protein; The stop region contains 1 stop codon, which marks the end of protein synthesis. In addition to this, GPLD1 has a highly conserved structure that maintains the specific activity of phospholipases during evolution.
Overall, GPLD1, as an important phospholipase enzyme, plays a key role in cellular phospholipid metabolism. Its specific structure and function make it an important research object for the study of phosphatidylinositol (PI) metabolism and regulation of cellular events. It is hoped that through the in-depth study of GPLD1, we can better understand the regulatory mechanism of cellular lipid metabolism and provide a theoretical basis for the prevention and prevention of related diseases.